Alpha-GPC, also known as alpha-glycerophosphocholine, is a phospholipid-like compound found in all tissues of the body, including the brain. Alpha-GPC can be readily converted to phosphatidylcholine, the most abundant phospholipid found in the body. In the brain, this is especially important as phosphatidylcholine plays an important role in cellular signaling and the synthesis of the neurotransmitter acetylcholine. As phospholipid metabolites change throughout normal aging processes, Alpha-GPC helps maintain cognitive function during aging. Randomized control trials have found that Alpha-GPC supplementation helps mental focus, recall, attention and cognitive function in both middle aged and elderly adults. Alpha-GPC is also a source of choline for the maintenance of good health. In addition to its role in the brain, choline has been found to have numerous biological functions in the body including involvement in methylation and cellular signaling pathways.
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