5-Hydroxytryptophan (5-HTP) is an intermediate in the natural synthesis of serotonin from the essential amino acid tryptophan. The enzyme tryptophan hydroxylase adds a hydroxyl group (OH) to tryptophan, forming the 5-HTP intermediate. In the body, 5-HTP is converted to serotonin with the removal of a carboxyl group (COOH) by a second enzyme. 5-HTP is involved in the regulation of endocrine and brain activity responsible for emotion and sleep/wake cycles. In clinical studies, administration of 5-HTP has been reported to improve rapid eye movement (REM) sleep duration and promote emotional well-being. The 5-HTP supplied in this supplement is derived from the Griffonia simplicifolia plant.
- Ages 18 and up
- Brain serotonin levels to support emotional well-being‡
5-HTP 50 mg
As a dietary supplement, take 1 capsule, 1-4 times daily, before meals, or as directed by a health professional.
5-HTP 100 mg
As a dietary supplement, take 1 capsule, 1-3 times daily, before meals.
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